abstract |
FIELD: chemistry. n SUBSTANCE: invention refers to benzamide 4-(phenyl-piperazin-methyl) derivatives of the general formula I in which R 1 - aryl, heteroaryl, selected from the group which includes difuryl, pyridyl and thienyl; R 2 - hydrogen or C 1-12 alkyl. The methods of preparation of the compounds, pharmaceutical composition on their basis and application while preparing medicines are described. n EFFECT: compounds can be applied to treatment of pain and functional gastroenteric upset. n 8 cl, 1 ex |