http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2326689-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_45b85eac1c9279077542f8fdb361fe1b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-37 |
| filingDate | 2007-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc433d75603d47e856754e0e58fdd578 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f5abe0660c68066ee8bbebef7b8139d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83aa8b3cb86b761e70e7ffaed75d09b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c85c95c50568a2d8a1901e74b95c2844 |
| publicationDate | 2008-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2326689-C1 |
| titleOfInvention | Method of human blood coagulation viii factor concentrate production and related product |
| abstract | FIELD: medicine; pharmacology. n SUBSTANCE: invention refers to method of human blood coagulation VIII factor production and related product. Method includes blood serum as cryoprecipitate, heparine added, PEG-4000, centrifugation, supernatant is added with tributyl phosphate and Twin-80, repeated centrifugation, sediment washed with sodium chloride, then it is dissolved in tris-HCl buffer with additives, let through column filled with gel and attached antibodies to Willebrand's factor, factor VIII elution, dialysis. Produced concentrate does not contain Willebrand's factor and has activity not less than 300 ME/mg of protein with purity not less 98% and contains albumin of concentration of 0.1%. Product is lyophilized with further processing. n EFFECT: product does not display any toxicity and cause allergic reaction. n 6 cl, 2 ex |
| priorityDate | 2007-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 95.