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filingDate 2006-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2008-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2008-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2326676-C1
titleOfInvention Method of systemic fat embolism development prevention in perioperative period
abstract FIELD: medicine. n SUBSTANCE: hepasol A in dosage 4.0-8.0 ml/kg and 5% glucose solution are injected separately in equal dosages 40 minutes before surgery. After main operation step is complete blood is microscopically tested for fat globules. In case 10 globules of size less than 5 mcm, or one or more globules of size more than 5 mcm are found totally within 8 microscopic field, test result is considered to be positive, and Hepasol A and 5% glucose solution introduction is prolonged. In case no globules found or those found are totally less than 10 in number of size less 5 mcm test result is considered to be negative, thus Hepasol A and 5% glucose solution introduction is stopped. Blood is repeatedly tested for fat globules in 12 hours after last introduction of Hepasol A. If positive test result for fat globules is registered, Hepasol A and 5% glucose solution introduction is recommenced, and in case double negative test result is registered, Hepasol A is not introduced. n EFFECT: method allows preventing of systemic fat embolism development in perioperative period. n 2 tbl, 1 ex
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