| abstract |
FIELD: chemistry. n SUBSTANCE: photosensitising agents obtained by reducing a double bond in porphyrinic macrocycle of sulphonated mesotetraphenylporphyrine, preferably disulphonated mesotetraphenylporphyrine, such as TPPS 2a . Resulting sulphonated mesotetraphenylchlorines are compounds of formula (I) , (where X stands for -SO 3 Н; each of n, p, q and r independently stands for 0 or 1; and sum of n, p, q and r is an integer from 1 to 4, preferably at least 2, in particular, 2 or 4), isomers or isomeric mixture. Compounds in accordance with the said invention and pharmaceutically suitable salts thereof have a high extinction coefficient in the region of 630 to 680 nm. n EFFECT: compounds are widely used as photosensitising agents for photochemical internalisation of molecules and photodynamic therapy. n 25 cl, 8 ex, 8 dwg |