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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5517
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filingDate 2002-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2008-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_406e6c9e0982dcd50d0d39a9a0315179
publicationDate 2008-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2322985-C2
titleOfInvention Using flumazenil in production of drug for treatment of cocaine abuse
abstract FIELD: medicine, narcology, pharmacy. n SUBSTANCE: invention proposes using flumazenil representing 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazol[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester for production of drug used in treatment of cocaine abuse, abstinence syndrome from cocaine and relapse of cocaine abuse. Agent is administrated in time periods from 1 to 15 min providing administration of from 0.1 to 0.3 mg of flumazenil that represents the therapeutically effective dose for treatment of cocaine abuse (variants), corresponding drugs (variants) of flumazenil and methods for treatment (variants). In this regimen in the dose 2 mg of flumazenil for less 1 h above 55% of gamma-glutamic acid receptors are occupied. Invention provides attenuation or removing symptoms of cocaine abuse and rapid recovery of psychophysiological functions. n EFFECT: valuable properties of drug and enhanced effectiveness of treatment. n 29 cl, 2 tbl
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2804834-C2
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