| abstract |
FIELD: organic chemistry, medicine, pharmacology. n SUBSTANCE: invention relates to a combination used in prophylaxis and/or treatment of thromboembolic diseases. Combination comprises N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-5-chloro-2-thiophene carboxamide of the formula (I): its pharmaceutically acceptable salts, hydrates or their mixtures and platelet aggregation inhibitor taken in subtherapeutic effective doses. Also, invention relates to a method for preparing this combination and a drug based on thereof. Proposed combination possesses the enhanced effectiveness. n EFFECT: improved and valuable medicinal properties of combination. n 4 cl, 2 tbl, 176 ex |