| abstract |
FIELD: medicine. n SUBSTANCE: described are injection compositions for administering of drug by implantation. Claimed composition contains low-molecular biodegradable biocompatible polymer, biocompatible water low-miscible solvent, which forms viscous gel with polymer and limits water absorption by implant, and pharmaceutical agent. Said solvent is selected from group containing aromatic alcohols, aromatic acid esters, aromatic ketones or mixture thereof. Gelled depot composition of present invention may be administered in mammalian body without surgery procedure and provides controlled release of pharmaceutical agent for about seven days. n EFFECT: new biodegradable depot compositions. n 30 cl, 13 dwg, 3 tbl, 12 ex |