http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2315624-C2
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-12 |
| filingDate | 2005-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2008-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2315624-C2 |
| titleOfInvention | Method for production of nanocolloid for producing of radiopharmaceutical agents |
| abstract | FIELD: pharmaceutical chemistry, radioactive nuclide diagnosis and therapy. n SUBSTANCE: claimed method includes sequential mixing under cooling solutions of sodium perrhenate, gelatin, sodium thiosulfate, and hydrochloric acid at sodium thiosulfate and sodium perrhenate molar ratio of 1.5-3.4. Obtained mixture is heated on boiling water bath under continuous stirring for 10 min, cooled, conditioned for 2-3 h, passed through chromatography column filled with anion exchange resin and containing sterilizing filter. Filtrate is collected up to acidic fraction breakthrough, pre-packed at aseptic conditions into sterile bottles for drugs and stored in refrigerator. Said nanocolloid has 80 % or more particles with size of 2-100 nm; 5 % or less particles with size of <20 nm; nanocolloid solution has storage stability of 6 months or more; radioactive preparation obtained on the base of such nanocolloid has radiochemical purity of 90 % or more wherein said radiochemical purity is kept for not less than 4 hours. n EFFECT: new radiopharmaceutical agents useful in lymphoscintigraphy. n 3 ex |
| priorityDate | 2005-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.