abstract |
FIELD: organic chemistry, medicine, pharmacology, pharmacy. n SUBSTANCE: invention relates to an antibacterial composition representing a complex of polyvinylpyrrolidone and metronidazol of the formula (I) wherein n = 76-276; m = 5-40, and containing 9-19% of metronidazol. Also, the invention relates to a method for preparing the indicated complex. The proposed composition provides maintaining the concentration of metronidazol at the therapeutic level for 48 h. n EFFECT: improved and valuable medicinal and pharmaceutical properties of composition. n 3 cl, 5 tbl, 5 ex |