| abstract |
FIELD: medicine, chemical-pharmaceutical industry, pharmacy. n SUBSTANCE: invention relates to using compound of the formula Z-linker-Z' (1) representing antagonist of chemokinine receptor CXCR4 for preparing a medicinal agent used in mobilization and collection of cell-precursors and/or stem cells in subject. The claimed invention describes also methods for increasing amount of cell-precursors and stem cells in animals using compounds that bind chemokinine receptor CXCR4. Using compound of the formula (1) allows enhancing effectiveness in treatment of HIV and to alleviate unfavorable effects on bone marrow in the process of chemotherapy carrying out. n EFFECT: improved methods for activation. n 19 cl, 12 tbl, 1 dwg, 4 ex |