http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2307163-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f958c875ddc35ca4e0c30c33b7fbb9d7 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 |
| filingDate | 2005-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abbce4600fc0b35d4d10566de4c06b9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d945ee626c65612b6c2f2f9404d7c74c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd45aef07b95d6862af5c76ea611cd00 |
| publicationDate | 2007-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2307163-C2 |
| titleOfInvention | RECOMBINANT FRAGMID DNA pHEN-TAB CONTAINING HUMAN SINGLE-STRAND ANTIBODY GENE, CAPABLE OF BINDING OF HUMAN TUMOR NECROSIS FACTOR ALPHA; RECOMBINANT Escherichia coli BACTERIA STRAIN AS PRODUCER OF HUMAN SINGLE-STRAND ANTIBODY AGAINST HUMAN TUMOR NECROSIS FACTOR ALPHA; RECOMBINANT SOLUBLE HUMAN SINGLE-STRAND ANTIBODY AGAINST HUMAN TUMOR NECROSIS FACTOR ALPHA |
| abstract | FIELD: gene engineering. n SUBSTANCE: recombinant fragmid DNA pHEN-TAB, containing unique human single-strand antibody gene is selected from constructed in vitro combinatorial phage library udder controlling of lactose operon promoter. Then Escherichia coli HB2151 cells are transformed with obtained fragmid DNA to produce recombinant bacterium strain Escherichia coli HB2151/pHEN-TAB as producer of human single-strand antibody capable of binding of human tumor necrosis factor alpha. Said antibody gas affinity constant of K af = 3.96±0.52x10 8 M -1 . n EFFECT: new soluble human single-strand antibody scTAB against human tumor necrosis factor alpha with high affinity. n 3 cl, 6 dwg, 6 ex |
| priorityDate | 2005-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 261.