abstract |
FIELD: complexing compounds. n SUBSTANCE: invention provides macrocyclic metal complexes, preparation thereof, and application thereof to form conjugates with biomolecules. Such conjugates are appropriate for use as contrast substances in NMR diagnostics and for use in radiotherapy. n EFFECT: enhanced relaxation ability and possibility to control it due to special ligands attached to macrocycles. n 12 cl, 2 tbl, 91 ex |