http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2293993-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a60f527ed873dae7ac4afa8c95a7ec03 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2005-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8a3413df283528ef3986efe0fe7e094 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9488581644727e5169283de603a88752 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2a5aca9a649cae57c3a901d176d8081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2bf8bb88955953ec3ad11ec61c3b07f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fec6e20eec7e581c5dba1fd4eceffe1b |
| publicationDate | 2007-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2293993-C1 |
| titleOfInvention | Method for determining burkholderia mallei capsular antigen immunogenicity level |
| abstract | FIELD: medicine. n SUBSTANCE: method involves applying test system comprising nonimmune peritoneal macrophages of guinea pig, avirulent non-capsuliferous B.mallei 10230-11-2 version cells and separate chromatographic antigenic capsule substance fractions of typical encapsulated B.mallei 10230 strain. Phagocytic activity indices give starting criterion for in vitro selecting immunogenic capsular antigen complexes of glanders pathogen with protection function as means for developing specific glanders prophylaxis. Avirulent non-capsuliferous B.mallei 10230-11-2 version cells are selected from typical encapsulated B.mallei 10230 strain by means of hyperimmune antiserum. The cells are introduced into glass flasks containing medium 199 with cattle serum and glass carrying attached nonimmune peritoneal macrophages of guinea pig. Some glanders pathogen antigen capsule fractions are added and test strain phagocytability is dynamically tested during 1-3 h. The phagocytability index value is interpreted in terms of capsular antigen complexes immunostimulation or immunosuppression levels. n EFFECT: high accuracy in estimating immunogenic activity level of some capsular glanders pathogen antigens. n 1 dwg, 1 tbl |
| priorityDate | 2005-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.