abstract |
FIELD: organic chemistry, medicine, pharmacy. n SUBSTANCE: invention relates to novel compounds of the formulas (1) , (2) , (3) or (4) , or isomers of compounds of formulas (2) and (3) wherein symbol values are determined in the invention claim. Also, invention relates to their pharmaceutically acceptable salts showing the improved solubility in aqueous media and improved bioavailability wherein indicated compounds possess the inhibitory activity with respect to secretion of gastric acid. n EFFECT: valuable medicinal properties of compounds. n 35 cl, 44 sch, 4 tbl, 165 ex |