abstract |
FIELD: organic chemistry, medicine, oncology, pharmacy. n SUBSTANCE: invention relates to using compound of the formula (I) as the first anti-tumor agent for preparing a medicinal preparation that in administration with the second anti-tumor agent prevents development of resistance of malignant cells to apoptosis as result of activation of NFKB by the indicated second anti-tumor agent. Invention provides enhancing effectiveness of treatment. n EFFECT: improved and valuable medicinal properties of agent. n 15 cl, 4 tbl, 3 ex |