http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2288472-C1

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00
filingDate 2005-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2006-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0890f266daf5315619a40f780d97e8ea
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publicationDate 2006-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2288472-C1
titleOfInvention Method for detecting concentration of antibodies in blood sera to pathogenic bacteria yersinia enterocolitica of serovars o:3, o:5 or o:6.30 at application of piezogravimetric immunosensor
abstract FIELD: immunology. n SUBSTANCE: through a flow microcell of 15-20 mcl volume one should pass the flow of phosphate buffer solution-carrier at the rate of about 30-90 mcl/min which should be supplemented with analyzed serumal sample at the volume of 200 mcl. The flow cell is supplied with a horizontally fixed piezogravimetric immunosensor at fluctuation frequency f m and receptor covering based upon one of the LPC Yersinia enterocolitica of serovars O:3, O:5 or O:6.30. Then it is necessary to register the binding LPC Yersinia enterocolitica of serovars O:3, O:5 or O:6.30 with antibodies according to the decrease of sensor's fluctuation frequency from f m up to f to detect the concentration of antibodies according to calibration graph being directly proportional against △f being equal to f m -f. Application of the present innovation enables to decrease the procedure of analysis up to 10 min and, also, carry out a re-usable analysis after regeneration of sorbed LPC at sensitivity being 1.3 mcg/ml and detect concentration of antibodies ranged 10-100 mcg/ml. n EFFECT: higher accuracy and efficiency of detection. n 8 ex, 1 tbl
priorityDate 2005-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 21.