http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2288225-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc4cb48da64d4d9d5c70bc737f012eef |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341 |
| filingDate | 2001-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44d20ab73c42f41fce45e85886eddfb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd6bdec0938f46b440a2024c1b4b2e93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddc48f27510a9f1c635fc413bee3c30b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ff6de791cf247df526730207309f166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b97051e8a2c7b64079cd8da93d4e90d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba085aa8bb737331cb55d34e35919951 |
| publicationDate | 2006-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2288225-C2 |
| titleOfInvention | Novel compounds possessing anti-inflammatory activity and pharmaceutical compositions comprising thereof |
| abstract | FIELD: organic chemistry, medicine, biochemistry, pharmacy. n SUBSTANCE: invention relates to novel compounds of the formula (I): wherein R 1 represents alkyl; R 2 represents halogen atom, formyl, substituted or unsubstituted alkyl, hydroxyl, (C 1 -C 6 )-alkoxy-group, halogenalkyl; or R and R 2 in common with atom to which they are bound form unsubstituted 5-7-membered structure of the formula: -CH 2 -(CH 2 ) n S- wherein n = 1 or 2; R 3 represents hydrogen atom, halogen atom or alkyl; R 4 represents alkoxy-group or unsubstituted aryl or aryl substituted with halogen atom, (C 1 -C 6 )-alkyl, halogenated (C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkoxy-group, (C 1 -C 6 )-alkylsulfonyl; R 5 represents hydrogen atom, hydroxyl, alkyl, alkenyl or alkoxy-group; R 6 represents hydrogen atom or alkyl; or R 5 and R 6 represent in common =O; X represents oxygen atom or -NR 8 wherein R 8 represents aryl substituted with halogen atom; m means a whole number in the range from 0 to 2, and its pharmaceutically acceptable salts. Also, invention relates to pharmaceutical compositions based on these compounds, method for treatment of diseases mediated by cyclooxygenase and to a method for inhibition of cyclooxygenase activity in cells. Invention provides preparing novel compounds possessing valuable biological effect. n EFFECT: valuable medicinal and biochemical properties of compounds and pharmaceutical compositions. n 11 cl, 98 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2785138-C1 |
| priorityDate | 2000-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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