abstract |
FIELD: organic chemistry, medicine. n SUBSTANCE: invention describes a novel derivative of 9-(2-diethylaminoethyl)-2-phenylimidazo[1,2-a]benzimidazole, namely its hydrobromide, eliciting properties of antagonist of serotonin 5-HT 3 -receptors that can be used in therapy of cytotoxic nausea and vomiting. New salt is low toxic and exceeds bemesetron by anti-serotonin activity that is a selective 5-HT 3 - antagonist. n EFFECT: improved and valuable medicinal properties of derivative. n 2 cl, 2 ex |