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publicationDate 2006-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2285006-C1
titleOfInvention 9-(2-DIETHYLAMINOETHYL)-2-PHENYLIMIDAZO[1,2-a]BENZIMIDAZOLE HYDROBROMIDE ELICITING PROPERTY OF SEROTONIN 5-HT3-RECEPTOR ANTAGONIST
abstract FIELD: organic chemistry, medicine. n SUBSTANCE: invention describes a novel derivative of 9-(2-diethylaminoethyl)-2-phenylimidazo[1,2-a]benzimidazole, namely its hydrobromide, eliciting properties of antagonist of serotonin 5-HT 3 -receptors that can be used in therapy of cytotoxic nausea and vomiting. New salt is low toxic and exceeds bemesetron by anti-serotonin activity that is a selective 5-HT 3 - antagonist. n EFFECT: improved and valuable medicinal properties of derivative. n 2 cl, 2 ex
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