| abstract |
FIELD: chemistry of peptides, medicine, pharmacy. n SUBSTANCE: invention relates to compound of the formula (I): wherein R 1 represents benzofuranyl substituted with halogen atom or styryl substituted with halogen atom; R 2 represents substituted hydroxyl substituted with mercapto-group or substituted sulfonyl, or its pharmaceutically acceptable salts. Compound of the formula (I) and its pharmaceutically acceptable salts possess the strong inhibitory effect on production of nitrogen oxide (NO) and can be useful in prophylaxis and/or treatment of NO-mediated diseases in humans and animals. n EFFECT: valuable medicinal and biochemical properties of compounds. |