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grantDate 2006-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2006-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2281289-C1
titleOfInvention METHOD FOR PREPARING 6β-FORMYL-B-NORCHOLESTANE-3β,5β-DIOL
abstract FIELD: organic chemistry, chemistry of steroids. n SUBSTANCE: invention relates to a new method for synthesis of 6β-formyl-B-norcholestane-3β,5β-diol of the formula (I): by constricting six-membered B-ring of cholesterol. Method involves photooxidation of cholesterol with air oxygen at irradiation by visible light in the presence of porphyrine photosensibilizing agent immobilized on low-molecular fraction of copolymer of tetrafluoroethylene and perfluoro-3,6-dioxo-5-methyl-6-sulfonylfluoride octene-1 in the mass ratio porphyrine photosensibilizing agent : cholesterol = 1:(12-15). As porphyrine photosensibilizing agent 5,10,15,20-tetraphenylporphyrine can be used. Method shows technological simplicity, it doesn't require rigid conditions and provides the high yield of the end product. n EFFECT: improved preparing method. n 2 cl, 3 ex
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