abstract |
FIELD: biotechnology. n SUBSTANCE: invention relates to method for stable cell transduction of hematopoesis system or hematopoesis stem cells. Claimed method includes simultaneous cell in vivo or in vitro contact with lentivirus vector and molecule bonding to cell surface. Method of present invention allows stable transduction more 75 % of cells over 14 days. Method for introduction of gene material into cell also is disclosed. n EFFECT: new method useful in medicine, virology, and gene engineering. n 40 cl, 28 dwg, 9 ex |