abstract |
FIELD: pharmacy. n SUBSTANCE: invention relates to the improved formulation of aripiprazole showing the reduced hygroscopicity. These formulations are not converted to hydrate and not loss the initial solubility being even the medicinal preparation comprising anhydrous apipiprazole crystals are stored for a long time. Also, invention describes method for preparing these formulation and pharmaceutical composition based on thereof. n EFFECT: improved and valuable pharmaceutical properties of agent. n 22 cl, 32 dwg, 7 tbl, 28 ex |