| abstract |
FIELD: organic chemistry, medicine, pharmacy. n SUBSTANCE: invention relates to compounds of the formula: or wherein x means 1, 2, 3 or 4; m means 1 or 2; n means 1 or 2; Q represents carbon atom (C) or nitrogen atom (N); A represents oxygen atom (O) or sulfur atom (S); R 1 represents lower alkyl; X represents -CH; R 2 represents hydrogen (H) or halogen atom; R 2a , R 2b and R 2c can be similar or different and they are chosen from hydrogen atom (H), alkyl, alkoxy-group or halogen atom; R 3 represents aryloxycarbonyl or alkoxyaryloxycarbonyl; Y represents -CO 2 R 4 wherein R 4 represents hydrogen atom (H) or alkyl, and including all their stereoisomers, their prodrugs as esters and their pharmaceutically acceptable salts. These compounds are useful antidiabetic and hypolipidemic agents and agents used against obesity also. n EFFECT: valuable medicinal properties of compounds. n 29 cl, 12 tbl, 587 ex |