http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2275354-C2
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-24 |
filingDate | 2001-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2006-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7676bc3c7c66afff8614e4d35abbe7f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3543ec33a3ad2460e68bd95bb5b387ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45fcc1b9f390db251b7ff4f434c0d077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88851c915a175622046b298c15750b52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38a09679758d2de9f60b130345118c9a |
publicationDate | 2006-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2275354-C2 |
titleOfInvention | Methods for preparing nateglynide crystal of b-type |
abstract | FIELD: organic chemistry, chemical technology, medicine, pharmacy. n SUBSTANCE: invention relates to methods for preparing nateglynide representing N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine that is used as a therapeutic agent in treatment of diabetes mellitus as it decreases blood glucose level effectively after oral administration. In particular, invention relates to methods for preparing nateglynide crystals of B-type practically free of crystals of H-type. Method involves drying solvated wetted nateglynide crystals at temperature 60°C and below up to complete removal of solvent and crystals are crystallized for their conversion to crystals of B-type at temperature from 60°C to 100°C. Nateglynide crystals of B-type can be obtained in industrial scale being without the simultaneous presence of other forms of crystalline polymorphism. n EFFECT: improved preparing methods. n 10 cl, 3 ex |
priorityDate | 2000-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.