http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2273645-C9
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2658d45a8e9c71b9598e2bf83242bab3 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 |
| filingDate | 1995-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df76c6f30dc4bbbab3f5b2eb7d5cabb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8082ad536343f85a7970a3af79d87aa4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84c63183528796c256f1c2f11cbd8ee4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84ccbb1fd925394adef642752e0f7813 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_862115d4708fa4da0b91cccbc7d17a27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88730b30f3c73b8ae12d8934bb8923ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a39be01ce3a92c17de88ccc3e9eb0cbb |
| publicationDate | 2006-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2273645-C9 |
| titleOfInvention | Obesity polypeptide (ob) (variants), its analogue (variants), and fused protein (variants), nucleic acid isolated molecule, dna molecule, cloning recombinant vector, expression recombinant vector, pharmaceutical composition, monoclonal and polyclonal antibody |
| abstract | FIELD: biotechnology, molecular biology, medicine. n SUBSTANCE: invention discloses amino acid sequences of human obesity polypeptide (OB) two isoforms possessing capacity for modulation of animal body mass, their signal peptide-containing precursors and analogues. Polypeptide isoforms are prepared as result of insertions, deletions and amino acid changes that retain activity typical for nonmodified forms of OB-polypeptides, and polyclonal and monoclonal antibodies interaction specifically with new agents modulating the body mass value also. Invention describes DNA sequences encoding these polypeptides and their analogues, vector structures comprising these sequences used for preparing recombinant forms of OB-polypeptides. Invention proposes using new polypeptides and their analogues as an active component in pharmaceutical compositions. Using this invention can promote to solving the problem for providing medicine, veterinary science and animal husbandry with effective agent used for decreasing the body mass value. Invention can be used in medicine for diagnosis and treatment of pathological states associated with disturbance of regulation of human body mass, and in animal husbandry and veterinary science. n EFFECT: valuable biological, medicinal and veterinary properties of polypeptide. n 23 cl, 71 dwg, 12 tbl, 17 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11584780-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11739345-B2 |
| priorityDate | 1994-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 918.