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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543
filingDate 2003-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2006-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0fcf3752586b25de145a0fe69acadb8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d5e14ed907ffdbe3571ca2c2edb0722
publicationDate 2006-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2271540-C2
titleOfInvention Method for production of biomagnetic immunosorbent for bacterial antigen detection (variants)
abstract FIELD: biotechnology, immunology, microbiology. n SUBSTANCE: freeze-dried 10-40 % cell slurries are treated singly or twice with 25-35 % iron sulfate solution. After repeat freeze drying treatment with 20-25 % ammonium aqueous solution is carried out. Then obtained magnetic cells are activated with 5 % glutaric aldehyde for 4 h. Further cells are treated with species-specific competent immunoglobulins from lemic, tularemia, or brucellosis serum containing 10 mg/ml of antibodies for 24±2 h. Method of present invention makes it possible to detect lemic bacteria, tularemia, and brucellosis in concentration of 10 3 -10 4 m.c./ml. Obtained biomagnetic immunosorbents may be stored for 2 years at 4-8° without losses of specific activity. n EFFECT: biomagnetic immunosorbents of improved sensitivity and prolonged storage-time. n 5 cl, 9 ex
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2756202-C1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2668688-C2
priorityDate 2003-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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