http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2271350-C2
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P- |
| filingDate | 2001-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_816427d9fa9f9abefe20d16f0a04371c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecd0b03413f8e02b06e5744402130904 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df4464fbc24ad6c93c057ebd7e49ccb5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08baf1dcadbed988bc34362664efabe1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa770171ea6e2f95ee119eba716fd088 |
| publicationDate | 2006-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2271350-C2 |
| titleOfInvention | Derivatives of acylphenylurea, pharmaceutical composition and method for its preparing |
| abstract | FIELD: organic chemistry, medicine, endocrinology, pharmacy. n SUBSTANCE: invention relates to new derivatives of acylphenylurea of the formula (I) and to their physiologically acceptable salts possessing property of glycogen phosphorylase inhibitors. In compound of the formula (I) A means phenyl and phenyl residue can be substituted three times with fluorine (F), chlorine (Cl), bromine (Br) atoms, -CF 3 , -NO 2 , -O-(C 1 -C 6 )-alkyl, -SO 2 -(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkyl, -COOH; R1 means hydrogen atom (H), (C 1 -C 6 )-alkyl; R2 means H, (C 1 -C 6 (-alkyl, -CO-(C 1 -C 6 )-alkyl; 3, R4, R5 and R6 mean independently of one another H, F, Cl, Br, -O(C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkyl, (C 3 -C 7 )-cycloalkyl, -COOH, -COO-(C 1 -C 6 )-alkyl; X means oxygen (O), sulfur (S) atom; R7 means (C 1 -C 10 )-alkylene-COOH, (C 1 -C 10 )-alkylene-COO-(C 1 -C 6 )-alkyl, (C 1 -C 10 )-alkylene-NH 2 , (C 1 -C 10 )-alkylene-NH-(C 1 -C 6 )-alkyl, (C 1 -C 10 )-alkylene-N-[(C 1 -C 6 )-alkyl] 2 , (C 1 -C 10 )-alkylene-B wherein B means piperidinyl or furyl. Also, invention relates to a pharmaceutical composition and a method for preparing the pharmaceutical composition. Proposed compounds can be used for preparing pharmaceutical composition useful for declining level of blood glucose and for treatment of diabetes mellitus type II. n EFFECT: improved preparing method, valuable medicinal properties of compounds and composition. n 7 cl, 2 sch, 2 tbl, 1 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2615136-C2 |
| priorityDate | 2000-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 186.