http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2269538-C1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
| filingDate | 2004-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ba9d39d6d26f5b6cf4256f0b7232b39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3957ae87dd76d61d3174ffd12a9515df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fae833dc903afab5dd162399abf96cfe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7db8d5ae40011b838a23dadc2978656e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e283402b1873ddaaba847c162866782e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1236434661083dc52f508b58f120c08b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c2d97ae5fc1f626288a0f3f3ce5dee6 |
| publicationDate | 2006-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2269538-C1 |
| titleOfInvention | SUBSTITUTED PYRIDO[4',3':5,6]PYRANO[2,3-d]PYRIMIDINES AND COMBINATORY LIBRARY |
| abstract | FIELD: organic chemistry of heterocyclic compounds, biology, medicine, pharmacy. n SUBSTANCE: invention relates to new substituted pyrido[4',3':5,6]pyrano[2,3-d]pyrimidines of the general formula (1): or (2): or their pharmaceutically acceptable salts, N-oxides or hydrate possessing physiologically active properties, in particular, eliciting ability to induce apoptosis in tumor cells causing their death. In the general formula (1) or (2) X represents sulfur or oxygen atom; Y represents sulfur atom, group -SO, group -SO 2 , group -NH or group -NR 6 ; R 1 represents aryl, substituted aryl, heteroaryl; R 2 and R 5 represent hydrogen atom, alkyl, allyl, substituted benzyl, group -CH 2 -C(O)R 3 , group -CH 2 -C(O)NR 3 R 4 wherein R 3 , R 4 and R 6 represent inert substitute. Also, invention relates to new combinatory libraries for search compound-leaders and candidates for medicinal compounds preparing by screening the combinatory libraries. n EFFECT: valuable medicinal properties of compounds. n 9 cl, 1 tbl, 9 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2547835-C1 |
| priorityDate | 2004-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.