http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2266539-C1

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Predicate Object
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C02F1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-18
filingDate 2004-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2005-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21317f60405705984cf6a027c661a04c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7eceb8e25ca981b3c8cd370692a14bb4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f91fabf3314eec68003f0ac1c619be5
publicationDate 2005-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2266539-C1
titleOfInvention METHOD OF DETERMINING TOXICITY OF AN AQUEOUS MEDIUM (OPTIONS), REAGENT FOR DETERMINING TOXICITY OF AN AQUEOUS MEDIUM, AND USE OF ANIMAL BRAIN PLASMA MEMBRANE Mg2+-ATPase
abstract FIELD: analytical methods in environmental protection and toxicology. n SUBSTANCE: subject of invention is drinking, natural, and waste water quality monitoring. Toxicity of aqueous medium is determined from variation in activity of animal brain plasma membrane Mg 2+ -ATPase activated by chlorine and/or bicarbonate ions. In one embodiment of invention, toxicity of aqueous medium is determined by mixing above plasma membranes with test aqueous medium adjusted to physiologic pH with phosphorus-free buffer followed by addition of solution containing Tris-ATP and magnesium ion source as well as chloride and/or bicarbonate ion(s) source, incubation until inorganic phosphorus is formed, and determination of toxicity from concentration of inorganic phosphorus. Brain plasma membranes used as indicator contain Mg 2+ -ATPase capable of being activated by chlorine and/or bicarbonate ions. n EFFECT: extended functional possibilities of method and use of reagent, increased sensitivity, and enabled determination of toxicity at lower concentration of various-type toxicants. n 20 cl, 6 tbl
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2680519-C1
priorityDate 2004-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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