http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2265018-C2
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-36 |
filingDate | 2002-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2005-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c86bd8bb85f18d80526ae3ade353182 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_335e5b457a247ab615e8b833d58a7879 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fe383a87f078615b58b498fd8f25dee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa2ef79cb164f1f938a777249e97b783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_144d6df471eabc46aef43a103450ad3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d2d7e554330ded09ba9f21c3514db94 |
publicationDate | 2005-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2265018-C2 |
titleOfInvention | Derivatives of benzimidazole and pharmaceutical compositions based on thereof |
abstract | FIELD: organic chemistry, pharmacy. n SUBSTANCE: invention relates to derivatives of benzimidazole of general formulae (IV) n and n For compounds of the formula (IV): R represents hydrogen atom, (C 1 -C 10 )-alkyl and others; D represents phenyl or azaphenyl; n = 0; A, B and Q represent hydrogen atom, (C 1 -C 10 )-alkyl and others; Z represents a bond, (C 1 -C 6 )-alkylene or -CH 2 O-; R 1 represents hydrogen atom, (C 1 -C 10 )-alkyl and others; R 2 represents hydrogen atom. For compounds of the formula (IVA): n = 0; Z represents a bond, -CH 2 -, -CH 2 O-, -CH 2 CH 2 -; R represents hydrogen atom or (C 1 -C 10 )-alkyl; R 1 represents hydrogen atom, (C 3 -C 12 )-cycloalkyl, benzyl and others; R 2 represents hydrogen atom. Compounds of formulae (IV) and (IVA) possess affinity with respect to nociceptin and μ-receptors and can be used in medicine. n EFFECT: valuable medicinal properties of compounds. n 18 cl, 5 tbl, 16 ex |
priorityDate | 2001-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1594.