http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2264390-C1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75 |
| filingDate | 2004-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2005-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9572708595679047d5306370447d4b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b43c51656c314bbc87e4657ec4b70bb0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5959bb49f8a33bf7cd71b5b42ced606d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17ab751cb535103291791b94a0a4dc3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e9e3c6dfbc58ad26ebbe05e655e151b |
| publicationDate | 2005-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2264390-C1 |
| titleOfInvention | 2-hydroxy-5,5-dimethyl-4-oxo-2-hexenoic acid n-41-methyl-21-pyridylamide eliciting hypertensive activity |
| abstract | FIELD: organic chemistry, chemical technology, medicine. n SUBSTANCE: invention relates to a new compound - 2-hydroxy-5,5-dimethyl-4-oxo-2-hexenoic acid N-4 1 -methyl-2 1 -pyridylamide of the formula: n . This compound is prepared by interaction of 2-hydroxy-5,5-dimethyl-4-oxo-2-hexenoic acid with 4-methyl-2-pyridylamine. Proposed compound can be used in medicine as a hypertensive agent. The hypertensive activity of this compound exceeds activity of standard compound - midodrine hydrochloride by 2-fold increase of arterial pressure value and by 3-fold by duration effect in combination with 2-fold reduced toxicity. n EFFECT: improved and valuable medicinal properties of compound. n 1 cl, 2 tbl, 1 ex |
| priorityDate | 2004-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.