Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-083 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
filingDate |
2000-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2005-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7609b0527a45931ab28223e9bf27c52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_913a69e94d61e0e76ea32288e115f2ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4816bdee521cab65e735cdf7241876d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce5dad9cd83ae6bf542e047bdb2fc489 |
publicationDate |
2005-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
RU-2260599-C2 |
titleOfInvention |
MODULATING AGENT FOR AGGREGATION OF β-AMYLOID FOR AGGREGATION INHIBITION OF NATURAL β-AMYLOID OR FOR TREATMENT OF SUBJECT WITH DISORDER ASSOCIATED WITH β-AMYLOIDOSIS, PHARMACEUTICAL COMPOSITION AND METHOD FOR DETECTION OF NATURAL β-AMYLOID PEPTIDE IN BIOLOGICAL SAMPLE |
abstract |
FIELD: chemistry of peptides, medicine. n SUBSTANCE: invention relates to compound of the structure: N-methyl-(D-Leu-D-Val-D-Phe-D-Phe-D-leu)-NH 2 designated for using as an active component in manufacturing a medicinal agent used for inhibition of natural β-amyloid peptides aggregation in patients suffering with disorder associated with β-amyloidosis and in treatment of Alzheimer's disease. Also, invention relates to a pharmaceutical composition, a method for inhibition of natural β-amyloid peptides, a method for detection of natural β-amyloid, a method for detection for the presence or absence of natural β-amyloid peptides in biological sample and to a method for treatment of patient with disorder associated with β-amyloidosis. n EFFECT: improved method for detecting, valuable medicinal properties of agent. n 14 cl, 5 tbl, 5 dwg, 9 ex |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2804336-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2438706-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2564125-C2 |
priorityDate |
1999-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |