| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1044
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y203-02013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-625 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
| filingDate |
2001-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2005-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57e7064fbc9e4dca909f8b2bd2ee111f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc1a63d36a10958b80bc5931dd162010
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_128447b0ed20045ce7f7634377726fc4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41d06ccbce6aa57f2a748d5de5892a0b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc82343c0506562b99777fc97e12765d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b3bf7b5b68f746c12df702da7fd35c6 |
| publicationDate |
2005-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2260051-C2 |
| titleOfInvention |
Modification of microorganism transglutaminase |
| abstract |
FIELD: biotechnology, in particular method for construction and production of mutant transglutaminases (MTG). n SUBSTANCE: invention relates to method for construction and production of mutant transglutaminases based on space structure of transglutaminase obtained from Streptoverticillium mobaraense, as well as to mutant MTG obtained by said method. Also disclosed are method for MTG modification based on space structure and modified transglutaminase with enhanced reactivity relative to substrate. Method of present invention makes it possible to predict MTG binding site to substrate on the base of space structure that is determined by MNG crystal X-ray analysis, and to design mutant transglutaminases by replacement, insertion or deletion of amino acid residues disposed on transglutaminase substrate-binding site. n EFFECT: new method for production and modification of mutant transglutaminases. n 6 cl, 60 dwg, 5 ex |
| priorityDate |
2000-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |