http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2260002-C2
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 |
| filingDate | 2003-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2005-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_283e1e6df5da23ee2ceeb9b37856e50b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55eb2effb717c19118a223520ee6afa1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7115fce03969e446b1f6c5642b231df6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_067ab9b1b4cba51c07c06a34824609ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fba2eb3ea819a790aee134ac4dcb31c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fece67dc8aa225bc027344be2183fd69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c2d97ae5fc1f626288a0f3f3ce5dee6 |
| publicationDate | 2005-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2260002-C2 |
| titleOfInvention | Substituted 5-sulfo-2-oxo-1,2-dihydroquinoline 4-carboxylic acids and their derivatives (variants) and focused library |
| abstract | FIELD: organic chemistry, chemical technology, biochemistry. n SUBSTANCE: invention relates to new substituted 6-sulfo-2-oxo-1,2-dihydroquinoline 4-carboxylic acids and their derivatives of the general formula (1): n eliciting physiological activity, in particular, capacity to inhibit activity of protein kinase, and also to intermediate compounds for their preparing and to the focused library, for search compound-leaders and medicinal candidates obtaining on the basis of screening combinatory libraries. In compounds of the general formula (1) R 1 represents hydrogen atom or electrophilic substitute; R 2 represents hydrogen atom or inert substitute; R 3 represents optionally substituted hydroxyl group, optionally substituted amino-group and optionally substituted azaheterocycle; R 4 represents optionally substituted amino-group and optionally substituted azaheterocycle. Also, invention relates to compounds of the general formula (1.1): n wherein R 1 , R 2 and R 3 have above given values; R 5 represents hydroxyl or chlorine atom, and to their applying for preparing compounds of the general formula (1.2): n and (1.3): n wherein R 1 , R 2 and R 4 have above given values. n EFFECT: valuable medicinal and biochemical properties of compounds. n 6 cl, 4 tbl, 5 ex |
| priorityDate | 2003-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 95.