abstract |
FIELD: organic chemistry, biochemistry, medicine, pharmacy. n SUBSTANCE: invention relates to methods for treatment of diseases or syndromes associated with metabolism of fatty acids and glucose and to new compounds and their pharmaceutically acceptable salts. Invention relates to applying new compounds and pharmaceutical compositions for treatment of cardiovascular diseases, diabetes mellitus, cancer diseases, acidosis and obesity by inhibition of activity of enzyme malonyl-CoA-decarboxylase. Indicated compounds correspond to formulae (I) and (II) wherein Y, C, R 1 , R 2 , R 6 and R 7 have values given in the invention claim. n EFFECT: valuable medicinal and biochemical properties of azoles. n 27 cl, 8 tbl |