http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2247125-C2
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J43-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
| filingDate | 2000-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2005-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bbed92f4384c858d26289bcbca954db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fad7962d0523b3c9ea4ca43b58a8f878 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa41acd286ad3b81effd5bff070f0029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_751cd12ad2e1ccdddc91a2f7f74cb22c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b13a25004048e8d25ba23485c2ecd80a |
| publicationDate | 2005-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2247125-C2 |
| titleOfInvention | Conjugates of 4-benzylaminoquinolines with bile acid and their heteroanalogs, method for their preparing and drugs based on these compounds |
| abstract | FIELD: organic chemistry, medicine, pharmacy. n SUBSTANCE: invention relates to the substituted 4-benzylaminoquinolines and their heteroanalogs of the general formula (I): P-L-G (I) wherein G means compound of the formula: G(I) wherein K means -OR(7), -NH-CH 2 -CH 2 -SO 3 H, -NH-CH 2 -CO 2 H wherein R(7) means hydrogen atom, CH 3 ; R1-R6 mean independently of one another hydrogen atom, -OR(10), -R(10) being one of residues R1-R6 means a bond with L always; R(10) means hydrogen atom, (C 1 -C 4 )-alkyl; L means (C 1 -C 15 )-alkyl being one or some structural CH 2 -fragments can be replaced for -C≡C-, -NR(11)-, -CO-, -O- wherein R(11) means hydrogen atom; P means: or wherein A means nitrogen atom (N); B means CH; D means CH; E means CH; R16-R24 mean independently of one another hydrogen atom, F, Cl atoms, (C 1 -C 4 )-alkyl being alkyl residues can be mono- or multiple-substituted with fluorine atom, NR(25)R(26), OR(25), COR(25), COOR(25), CONR(25)R(26) being one of residues R16-R(24) means a bond with L always; R25 and R26 mean independently of one another hydrogen atom, (C 1 -C 4 )-alkyl or benzyl. Also, invention relates to their pharmaceutically acceptable salts. Also, invention relates to a method for their preparing and to a drug based on thereof for prophylaxis of supersaturation of bile with cholesterol. Invention provides preparing new compounds and a drug based on thereof that can be used for prophylaxis and treatment of patients suffering with gallstones. n EFFECT: improved preparing method, valuable medicinal properties of compounds and drugs. n 10 cl, 32 ex |
| priorityDate | 1999-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 175.