| abstract |
FIELD: organic synthesis. n SUBSTANCE: invention provides substituted 7-acylaminocephalosporins of formula I: n (I), where W denotes CH or B; V denotes NO; R 1 hydrogen or С 1 -С 4 -alkyl; R 3 hydrogen or ester residue; and R 2 one of the following groups: , , , , in which X, R 5 , R 6 , R' 6 , R 7 , and Hal have meanings indicated in claims, in free state, in the form of salts and/or solvates, or, if such forms are stable, in the form of internal salt, quaternary salt, or their hydrates, possessing antimicrobial activity. Invention also discloses a method for preparing such compounds and a pharmaceutical connected containing them. n EFFECT: increased choice of antimicrobial preparations. n 13 cl, 10 tbl, 225 ex |