http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2232989-C1
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-531 |
filingDate | 2002-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2004-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af01928fd3a48b4db0f4010641227879 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54b915174ce50f7215472101fc03f099 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a7840e029482ae62fb5afdabc77bd87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_250cd0cde6b2a01bbb418d3efe435ef6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a14bdaf69294e64da70d14c5191cd64 |
publicationDate | 2004-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2232989-C1 |
titleOfInvention | Method for preparing test-system for determination of helicobacter pylori cytotoxin-associated protein antigens in biological material in infected patients by co-agglutination reaction |
abstract | FIELD: medicine, immunology. n SUBSTANCE: invention can be used in diagnosis of diseases associated with H. pylori using co-agglutination reaction. As material for preparing anti-toxic rabbit helicobacter serum the homogenate from chicken embryos infected with the strain H. pylori NCTC 11637 (VAC-A + , CAG-A + ) and died for two days is used. Prepared serum contains mainly antibodies raised to large-molecular proteins (above 90 kDa), among them, to cytotoxin-associated CAG-A protein exhibiting high immunogenicity. On the basis of this serum Hp-tox-diagnosticum (test-system) is made for carrying out the co-agglutination reaction on plates that shows high sensitivity and specificity. Diagnosticum allows detecting antigens of large-molecular proteins in H. pylori, among them, proteins VAC-A and CAG-A being in human biological material directly (feces, saliva, circulating immune complexes). The application of method provides simplifying and accelerating the preparing test-system for carrying out the co-agglutination reaction. n EFFECT: improved preparing test-system. n 2 cl, 11 dwg, 2 tbl, 6 ex |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2630651-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2630651-C9 |
priorityDate | 2002-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.