| abstract |
FIELD: organic chemistry, medicine, pharmacy. n SUBSTANCE: invention relates to glucopyranosyloxypyrazole derivative of the formula (I) n n n n wherein R 1 represents hydrogen atom or lower alkyl group; one among Q 1 and T 1 represents group of the formula (II) n n n n while another of them represents lower alkyl group or halogen(lower alkyl) group; R 2 represents hydrogen atom, lower alkyl group, lower alkoxy-group, lower alkylthio-group, halogen(lower alkyl) group or halogen atom, or its pharmaceutically acceptable salts. Compounds act as inhibitors of human SGLT2 and can be used as agents for prophylaxis or treatment of diabetes mellitus, diabetic complications or obesity. Also, invention relates to pharmaceutical compositions containing proposed compounds and intermediate compounds used for their preparing. n EFFECT: improved preparing method, valuable medicinal properties of compounds. n 8 cl, 3 tbl, 73 ex |