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filingDate 1998-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2004-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55f42ff55f363053a77cd68f9973118c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_784462c5cce38dcb965a5a74c6d64c60
publicationDate 2004-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2232193-C2
titleOfInvention Method for preparing amide
abstract FIELD: organic chemistry, chemical technology, biochemistry. n SUBSTANCE: method for preparing amide from acrylonitrile involves chemical treatment of acrylonitrile-containing composition followed by effect on indicated acrylonitrile with nitrile hydratase. After chemical treatment the concentration of hydrocyanic acid in acrylonitrile-containing composition is reduced to 3 ppm or less. Chemical treatment can involve the process for conversion of hydrocyanic acid to metal chelate, contacting with ion-exchange resin or treatment under alkaline conditions. In particular case, method involves nitrile hydratase obtained from Rhodococcus rhodochrous. Method provides effective inhibition of deactivation of nitrile hydratase due to reducing the concentration of hydrocyanic acid in acrylonitrile-containing composition. This provides reducing enzyme amount required for carrying out the reaction. n EFFECT: improved preparing method. n 7 cl, 3 tbl, 7 ex
priorityDate 1997-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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