abstract |
FIELD: organic chemistry, medicine, pharmacy. n SUBSTANCE: invention relates to derivatives of imidazole of the formula (1) n n n n wherein X, Y, R, R 2 , R 3 and R 4 are given in the invention claim. These compounds are selective agonists with respect to adrenoceptors of subtype(s) α2B or α2B/α2C. Also, invention describes a method for administration of pharmaceutical composition and method for treatment based on these compounds. n EFFECT: improved administration and treatment methods, valuable properties of compounds. n 86 cl, 6 tbl, 67 ex |