| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
| filingDate |
2002-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_965ec3b75f53f11dcb597e70782272df
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_872b37d078cfce91f22c061cedc0ef95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f24d49db0e1bfde7f4f35fedfaec0c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43d903998a7247bcaf7302d3f7dd3e18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_313d9d2e294ef2912121fcaa9a09a7a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_117266d44d08ea01094a81949b7e0aac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1bf22d1ee2269fd62cde8f94772fb92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dc0bea40e6c0dab0407f73bf75b1ccd |
| publicationDate |
2004-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2230118-C2 |
| titleOfInvention |
METHOD FOR PREPARING 1-β-D-RIBOFURANOSYL-1,2,4-TRIAZOLE-3-CARBOXAMIDE (RIB AVIRIN) |
| abstract |
FIELD: organic chemistry, biotechnology, pharmacy. SUBSTANCE: invention relates to manufacturing antiviral compounds. Method for preparing ribavirin involved enzymatic trans-glycosylation reaction of 1,2,4-triazole-3-carboxamide followed by isolation of the end product. The trans-glycosylation reaction is carried out in the presence of recombinant purine-nucleoside phosphorylase from E. coli BL21 (DE3)/pERPUPHO1 immobilized on the aminopropylated silochrome. Method provides simplifying technology and using enzyme for 15 industrial cycles. EFFECT: improved preparing method. 4 dwg, 2 ex |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101974585-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2480218-C1 |
| priorityDate |
2002-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |