| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-245 |
| filingDate |
2001-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b7c17a61e35dc70065fb6b641a085c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f5455fecf9faca2a7061292cb9026a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba5df7cbbf9380abaaec8623d3d3342e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0656919e0a255212de63ceb35feb3cb0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bd09c944761cb8f7294ac408935a32d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6edb4f546f1504d80d7afc3157537bb |
| publicationDate |
2004-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2230116-C2 |
| titleOfInvention |
VECTOR FOR EXPRESSION AND SECRETION OF HUMAN ALPHA-INTERFERON (HIFN(hIFNα)), STR AIN ESCHERICHIA COLI FOR EXPRESSION AND SECRETION OF HIFNhIFNα, (VARIANTS) AND METHOD FOR PRODUCING HIFNhIFNα, |
| abstract |
FIELD: biotechnology, protein engineering, molecular biology. SUBSTANCE: invention relates to producing recombinant human interferons. Expressing vector for secretory producing human alpha-interferon (hIFNhIFNα) comprises polynucleotide encoding the modified signal sequence of thermostable E. coli enterotoxin II and polynucleotide encoding hINFhIFNα ligated with its 3-end. Vector is used in method for secretory producing human interferon by transformation the strain E. coli and culturing the indicated strain. Method provides secreting the soluble form of active hIFNhIFNα no comprising the additional methionine residue at its N-end into E. coli cell periplasm. EFFECT: valuable properties of vector and strain. 13 cl, 6 dwg, 1 tbl, 5 ex |
| priorityDate |
2000-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |