| abstract |
FIELD: biotechnology, antibiotics, microbiology, pharmacy. SUBSTANCE: invention relates to producing antibiotics, namely to the compound vancoresmycin that is prepared by culturing microorganism Amycolatopsis of species HIL-006734 (DSM 12216) and to its pharmaceutically acceptable salts (empirical formula and structural formula are given in text). Invention relates also to method for preparing vancoresmycin, to microorganism HIL-006734 (DSM 12216), to application of vancoresmycin and its pharmaceutically acceptable salts as medicinal agents, in particular, to their using as antibiotics and to pharmaceutical compositions comprising vancoresmycin or its pharmaceutically acceptable salt. Vancoresmycin acts against strains of Staphylococcus aureus that are resistant to vancomycin and teicoplanin that results to enhancement of treatment of infections caused by MRSA (methicillin-resistant Staphylococcus). EFFECT: valuable medicinal properties of vancoresmycin. 5 cl, 3 tbl, 5 dwg, 6 ex |