http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2214412-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea01481e494bd4cde60f022320fe3c47 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-26 |
| filingDate | 1997-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e450cfbeb4cbb4ab3baa9d45c3c06e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46765f76ae9ea6db25233d6de12e6db1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98083b3d39339d43644d9fbd94e18537 |
| publicationDate | 2003-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2214412-C2 |
| titleOfInvention | Derivatives of 8-pyridono[5,6-g]quinoline, pharmaceutical composition and method for control with their using |
| abstract | FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes novel derivatives of 8-pyridono[5,6-g] quinoline of the formulas (I) , or (III) , or (IV) wherein R 1 is hydrogen, fluorine, chlorine, bromine, iodine atom; R 2 is CF 3 CF 2 H; R 3 is hydrogen atom; R 4 and R 5 each independently means hydrogen atom, C 1 -C 4 -alkyl; R 6 and mean hydrogen atom; R 8 is hydrogen atom, C 1 -C 4 -alkyl; R 9 -R 18 each means hydrogen atom; R 19 means fluorine atom or NO 2 ; R 24 is hydrogen atom, C 1 -C 4 -alkyl, NO 2 ; R 25 is hydrogen atom, C 1 -C 4 -alkyl; R 26 is hydrogen atom, C 1 -C 6 -alkyl; R 27 and R 28 each independently means hydrogen atom or C 1 -C 4 -alkyl; m = 1; n = 0 or 1; o = 0 or 1; Y is oxygen atom; Z is NH, NR 22 ; R 22 is C 1 -C 4 -alkyl, and also pharmaceutical composition for effect on activity of androgenic receptors. Invention describes method of effect on activity of androgenic receptors, method for modulation process mediated by androgenic receptors, method for treatment of patient involving modulation of process mediated by androgenic receptors, method for treatment of patient needing androgen-receptor therapy using derivatives of 8-pyridono[5,6-g] quinoline. Proposed compounds are antagonists and agonists of androgenic receptors and can be used in treatment and/or modulation of acnes, male baldness, hirsutism, hypogonadism, hyperplasia of prostate and hormone-dependent cancers. EFFECT: valuable medicinal properties of compounds. 36 cl, 4 tbl, 31 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2523279-C2 |
| priorityDate | 1996-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.