http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2214274-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_419a7fbbbd60ee7abc22568d5546740f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17568f4f72f48fe62a705eaac7d10073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd14e13a94eeb4f0ec11ef749e55f4f0 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
| filingDate | 2001-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdeb2057b030a1d7173ef4b48da5559a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_053e1ed645b1fb3d0b07a7b7acdc54f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2119b1f85215fad4e40bfd9e5144ff21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_577cfbb630bf0ce0fb1cb6ec90c7493a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27d05cef6fad06c9292d44e110882818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a804c3c3a39445d93b5a1ba4832b9429 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f16cd19b2eea5e80a2775f5765b500c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ceeed2a90ebeb5fb217651801a47a485 |
| publicationDate | 2003-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2214274-C2 |
| titleOfInvention | Immunogenic composition containing chimeric hiv polypeptide, polypeptides and test-system for detection of antibodies raised to hiv |
| abstract | FIELD: medicine, biotechnology. SUBSTANCE: invention relates to immunogenic composition containing chimeric HIV polypeptide, method for induction of immune response to HIV 1 and HIV 1/2, chimeric polypeptide HIV 1 and HIV 1/2, DNA molecule encoding chimeric polypeptide, plasmid vector for expression of chimeric polypeptide, polyclonal antibodies raised to HIV 1 or HIV 1/2 and diagnostic test-system for detection of antibodies raised to HIV 1 and HIV 2. Invention involves immunogenic composition based on chimeric polypeptides HIV 1 or HIV 1/2 representing full-sized protein p24 fused with immunodominant fragment gp 41 of site 575-616 or taken among them (rec 24-41) or fused with immunodominant fragment gp 36 of the same site or taken among them (rec 24-36). Indicated composition is able to induce the strong immune response to HIV 1 or HIV 2. Invention involves also the gene construction able to expression of indicated chimeric polypeptides in E. coli cells and diagnostic test-system for detection of antibodies raised to HIV 1 and HIV 2. The advantage of invention involves the development of gene construction allowing expression the chimeric recombinant protein that contains a full-sized polypeptide as a component of a single polypeptide chain and related by its conformation to viral protein p24 and immunogenic protein fragment of HIV 1 or HIV 2 envelope. Indicated recombinant proteins are able to induce strong immune response to HIV 1 or HIV 1/2 that allows using these chimeric polypeptides both for creation of diagnostic test-systems and for their recommendation for development of vaccine preparations. EFFECT: valuable properties of composition. 18 cl, 3 tbl, 5 dwg, 10 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8992934-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9675686-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2475264-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7765813-B2 |
| priorityDate | 2001-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 210.