| abstract |
FIELD: organic chemistry, biochemistry, medicine. SUBSTANCE: invention proposes an agent donor of nitrogen oxide activating soluble form of enzyme guanylate cyclase. Indicated agent inhibits aggregation of platelets, shows spasmolytic and vasodilating agent and it represents 3,6-bis- (4-aminofurazan-3-yl)-1,4,2,5-dioxadiazine of the formula (I) . Invention can be used in clinic as a spasmolytic and vasodilating agent and, in contrast to furoxane, it does not show significant effect on arterial blood pressure that suggests the possibility of its directed local using. EFFECT: valuable medicinal properties of agent. 1 dwg, 9 ex |