| abstract |
FIELD: medicine, pharmaceutical technology, pharmacy. SUBSTANCE: invention relates to tablet with enterosoluble coating and method of its making. Tablet comprises medicinal agent exhibiting sensitivity to low values of medium pH lower 3, for example, 2',3'-dideoxyinosine, enterosoluble coating prepared from copolymer of methacrylic acid and plasticizer. Tablets can be made of different size and can be intaken orally singly; or multiple tablets to provide the required dose can be incapsulated into soluble capsule. Tablets exhibit excellent stability against decomposition at pH lower 3 and excellent properties providing release of medicinal substance at pH above 4.2. EFFECT: improved properties of tablet. 40 cl, 4 tbl |