| abstract |
FIELD: medicine, pharmacy. SUBSTANCE: invention relates to rapidly cleaving pharmaceutical medicinal form for initial intake containing medicinal agent and combination of four excipients consisting of superdisintegrating agent, dispersant, distributing agent promoting to distribution of component and binding agent. Calcium silicate is taken as dispersing agent and medicinal agent is taken among group consisting of aripiprazol, entecavir, cefprozil, pravastatin, captopril, irbesrtan and omapatrilat and can involve other usual components, for example, sweetening agents and aromatic principles. Granules show advantage as they are stable and can be prepared without solvents and do not require special conditions and special handling. Medicinal forms, especially tablets, made from their using conventional equipment are decomposed into mouth for less 25 s. EFFECT: improved properties of medicinal form. 18 cl, 19 tbl, 9 ex |