| abstract |
FIELD: medicine. SUBSTANCE: invention relates to etiotropic chemotherapy of viral infections, in part, agent used for inhibition of HIV and CMV infections and method of their inhibition. Method involves application of amino acid and dipeptide derivatives of fullerene of the general formula C 60 -X where C 60 means fullerene nucleus; X means NH-CHR-COOH, NH-(CH 2 ) n -COOH, NH-CHR-CO-NH-CHR-COOH where n = 2-6; R means by-side radical of natural amino acid or dipeptide as agent for inhibition of viral infections, in part, HIV and CMV infections. Method of application of water-soluble amino acid or dipeptide derivatives of fullerene of the general formula C 60' -X as agent for inhibition of viral infections involves its effect on infected cellular cultures in vitro with effective inhibitory dose. EFFECT: enhanced inhibitory activity of agent. 20 cl, 1 tbl |